Antagonism of P2Y12 or GPIIb/IIIa receptors reduces platelet-mediated myocardial injury after ischaemia and reperfusion in isolated rat hearts - Barrabés, José A; Inserte, Javier; Mirabet, Maribel; Quiroga, Adoración; Hernando, Victor; Figueras, Jaume; Garcia-Dorado, David (Thrombosis and haemostasis, 2010)
Keywords: Abciximab; Adenosine Monophosphate - analogs & derivatives; Adenosine Monophosphate - pharmacology; Animals; Antibodies, Monoclonal - pharmacology; Blood Platelets - drug effects; Blood Platelets - metabolism; Blood Platelets - pathology; Female; Humans; Immunoglobulin Fab Fragments - pharmacology; Male; Middle Aged; Myocardial Infarction - drug therapy; Myocardial Infarction - pathology; Myocardial Infarction - physiopathology; Myocardium - metabolism; Myocardium - pathology; P-Selectin - genetics; P-Selectin - metabolism; Platelet Activation - drug effects; Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2 - metabolism; Reperfusion Injury; Ventricular Function, Left - drug effects