Cardiac fibrosis in end-stage human heart failure and the cardiac natriuretic peptide guanylyl cyclase system: Regulation and therapeutic implications - Ichiki, Tomoko; Schirger, John A.; Huntley, Brenda K.; Brozovich, Frank V.; Maleszewski, Joseph J.; Sandberg, Sharon M.; Sangaralingham, S. Jeson; Park, Soon J.; Burnett, John C. (Journal of molecular and cellular cardiology, 2014)
Keywords: Adult; Cardiovascular; Collagen Type I - genetics; Collagen Type I - metabolism; Female; Fibrosis; Guanylate Cyclase - metabolism; Heart failure; Heart Failure - enzymology; Heart Failure - pathology; Heart Failure - therapy; Heart Ventricles - metabolism; Heart Ventricles - pathology; Heart-assist device; Humans; Male; Middle Aged; Myocardium - metabolism; Myocardium - pathology; Natriuretic Peptide, Brain - genetics; Natriuretic Peptide, Brain - metabolism; Natriuretic peptides; Receptors, Atrial Natriuretic Factor - genetics; Receptors, Atrial Natriuretic Factor - metabolism; RNA, Messenger - genetics; RNA, Messenger - metabolism; Heart failure; Col; NP; cGMP; LV; LVAD; CFs; TGF; NPR-C; Fibrosis; GC; Heart-assist device; HF; Natriuretic peptides; heart failure; cyclic guanosine monophosphate; natriuretic peptide receptor C; cardiac fibroblasts; left ventricle; collagen; natriuretic peptide; TGF beta-1; guanylyl cyclase; left ventricular assist device