Autophagy and UPR in alpha-crystallin mutant knock-in mouse models of hereditary cataracts - Andley, Usha P.; Goldman, Joshua W. (Biochimica et biophysica acta, 2016)
Keywords: adults; Aging - genetics; animal models; Animals; Autophagy; Autophagy - genetics; Cataract; Cataract - genetics; Cataract - pathology; cell structures; Crystallin; crystallins; Crystallins - genetics; Disease Models, Animal; electron microscopy; epithelium; fiber cells; gene expression regulation; Gene Knock-In Techniques; heterozygosity; immunoblotting; immunohistochemistry; Knock-in mouse; Lens, Crystalline - metabolism; Lens, Crystalline - pathology; Mice; mutants; Mutation; opacity; phenotype; protein degradation; Unfolded protein response; Unfolded Protein Response - genetics; water solubility; Cataract; Crystallin; Knock-in mouse; Mutation; Autophagy; Unfolded protein response