Usefulness of post mortem determination of serum tryptase, histamine and diamine oxidase in the diagnosis of fatal anaphylaxis

• Published in: Forensic science international Vol. 212; no. 1; pp. 96 - 101
• Main Authors: Mayer, D.E., Krauskopf, A., Hemmer, W., Moritz, K., Jarisch, R., Reiter, C.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Ireland Ltd 10.10.2011; Elsevier; Elsevier Limited; Elsevier Sequoia S.A
• Subjects: Allergies; Amine Oxidase (Copper-Containing) - analysis; Amine Oxidase (Copper-Containing) - blood; Anaphylaxis; Anaphylaxis - blood; Anaphylaxis - etiology; Anaphylaxis - mortality; Anesthesia; Autopsy; Bees; Biological and medical sciences; Case-Control Studies; Cause of Death; Diamine oxidase; Female; Forensic medicine; Forensic Medicine - methods; Forensic sciences; General aspects; Histamine; Histamine - analysis; Histamine - blood; Humans; Hymenoptera stings; Insect Bites and Stings - complications; Investigative techniques, diagnostic techniques (general aspects); Male; Medical diagnosis; Medical sciences; Middle Aged; Pathology; Public health. Hygiene; Public health. Hygiene-occupational medicine; Reference Values; Sensitivity and Specificity; Tryptase; Tryptases - analysis; Tryptases - blood; Venom; Histamine; Anaphylaxis; Hymenoptera stings; Tryptase; Diamine oxidase; Allergy; Fatal curse; Insecta; Sting; Forensic aspect; Determination; Serum; Diagnosis; Immunopathology; Serine endopeptidases; Forensic science; Enzyme; Legal medicine; Postmortem; Amine oxidase (copper-containing); Peptidases; Arthropoda; Hydrolases; Oxidoreductases; Invertebrata; Hymenoptera

The diagnosis of fatal anaphylaxis can be difficult for clinical features may not always be evident in necropsy. Therefore post mortem determination of tryptase and other blood parameters can be helpful in verifying the diagnosis. We compared post mortem tryptase, histamine and diamine oxidase (DAO)...