Gut microbiota promote the inflammatory response in the pathogenesis of systemic lupus erythematosus

• Published in: Molecular medicine (Cambridge, Mass.) Vol. 25; no. 1; pp. 35 - 16
• Main Authors: Ma, Yiyangzi, Xu, Xiaoxue, Li, Mengtao, Cai, Jun, Wei, Qiang, Niu, Haitao
• Format: Journal Article
• Language: English
• Published: England BioMed Central 01.08.2019; BMC
• Subjects: Antibodies; Discriminant analysis; Disease; Fecal microbiota transplantation2; Feces; Gene expression; Genomes; Gut microbiota; Gut microbiota1; Hypotheses; Immune response; Immune response4; Immune system; Laboratory animals; Lupus; Lupus susceptibility gene5; Medical research; Microbiota; Pathogenesis; Software; Systemic lupus erythematosus3; Taxonomy; United States > US; Fecal microbiota transplantation2; Immune response4; Gut microbiota1; Lupus susceptibility gene5; Systemic lupus erythematosus3

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease whose onset and progression are affected by genetic and environmental factors. The purpose of this study is to identify the influence of gut microbiota in the pathogenesis of SLE, and to investigate the mechanism involved. Fecal micr...