New approach to determine the healthy immune variations by combining clustering methods

• Published in: Scientific reports Vol. 11; no. 1; pp. 8917 - 10
• Main Authors: Liefferinckx, Claire, De Grève, Zacharie, Toubeau, Jean-François, Perée, Hélène, Quertinmont, Eric, Tafciu, Vjola, Minsart, Charlotte, Rahmouni, Souad, Georges, Michel, Vallée, François, Franchimont, Denis
• Format: Journal Article Web Resource
• Language: English
• Published: London Nature Publishing Group UK 26.04.2021; Nature Publishing Group; Nature Portfolio
• Subjects: 631/114; 631/114/2404; Algorithms; Blood; Clustering; Cortisol; Cytomegalovirus; Datasets; Disease; Environmental factors; Epstein-Barr virus; Gastroenterology; Hormones; Human health sciences; Humanities and Social Sciences; Immune system; Immunologie & maladie infectieuse; Immunology & infectious disease; Inflammatory diseases; multidisciplinary; Principal components analysis; Proteins; Science; Science (multidisciplinary); Sciences de la santé humaine; Testosterone; Variability; Variation

Immune-mediated inflammatory diseases are characterized by variability in disease presentation and severity but studying it is a challenging task. Defining the limits of a healthy immune system is therefore a prior step to capture variability in disease conditions. The goal of this study is to chara...