Metabolomic Profiling Reveals Cellular Reprogramming of B-Cell Lymphoma by a Lysine Deacetylase Inhibitor through the Choline Pathway - Pera, Benet; Krumsiek, Jan; Assouline, Sarit E.; Marullo, Rossella; Patel, Jayeshkumar; Phillip, Jude M.; Román, Lidia; Mann, Koren K.; Cerchietti, Leandro (EBioMedicine, 2018)
Keywords: Advanced Basic Science; Animals; Cell Line, Tumor; Cellular Reprogramming - drug effects; Choline - metabolism; Choline Kinase - metabolism; Choline pathway; DLBCL; Histone Deacetylase Inhibitors - pharmacology; Humans; Hydroxamic Acids - pharmacology; Indoles - pharmacology; Internal Medicine; Lymphoma, Large B-Cell, Diffuse - metabolism; Lymphoma, Large B-Cell, Diffuse - pathology; Lysine - metabolism; Male; Metabolome - drug effects; Metabolomics; Metabolomics - methods; Mice; Morpholines - pharmacology; Panobinostat; PI3K; Pyrimidines - pharmacology; Research Paper; Signal Transduction - drug effects; Xenograft Model Antitumor Assays; Panobinostat; Metabolomics; DLBCL; PI3K; Choline pathway