896-P: Positive Effect of Acute and Chronic Effects of Oral Ketones in Subjects with HFrEF and Diabetes

• Published in: Diabetes (New York, N.Y.) Vol. 74; no. Supplement_1; p. 1
• Main Authors: ACOSTA, FRANCISCA M., CHIDURALA, SUCHIT, FRAUSTO, PAOLA, MARQUEZ NAJERA, GUILLERMO, MOODY, ALEXANDER, TODD, BYRON, HU, BEVERLY, ROLLINS, CAITLYN, JUAREZ, DEANNA, ESCOBAR VASCO, MARIA, CLARKE, GEOFFREY D., SOLIS-HERRERA, CAROLINA
• Format: Journal Article
• Language: English
• Published: New York American Diabetes Association 20.06.2025
• Subjects: Blood levels; Cardiac muscle; Chronic effects; Diabetes mellitus; Dosage; Energy resources; Ketones; Skeletal muscle

Introduction and Objective: Ketones are energy substrates, serving as a "superfuel" for the heart, skeletal muscle, etc.. Our previous work showed that 3-hour intravenous (IV) exogenous ketones (KE) improved left ventricular function in T2D patients with HFrEF by up to 6%, dose-dependently...