Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression - Bernard, R; Kerman, I A; Thompson, R C; Jones, E G; Bunney, W E; Barchas, J D; Schatzberg, A F; Myers, R M; Akil, H; Watson, S J (Molecular psychiatry, 2011)
Keywords: 631/208/191/2018; 631/378/1385/1611; 692/699/476/1414; Adolescent; Adult; Adult and adolescent clinical studies; Aged; Antidepressants; Astrocytes; Autopsy; Behavioral Sciences; Biological and medical sciences; Biological Psychology; Bipolar disorder; Brain; Brain stem; Cellular signal transduction; Cognitive ability; Depression; Depressive Disorder, Major - pathology; Development and progression; DNA microarrays; Drugs; Emotional disorders; Etiology; Female; Fibroblast growth factor receptors; Forebrain; Gene expression; Gene Expression Profiling - methods; Gene Expression Regulation; Genetic aspects; Glutamate; Glutamate Plasma Membrane Transport Proteins; Glutamic Acid - genetics; Glutamic Acid - metabolism; Growth factors; Humans; Hybridization; Innervation; Intercellular Signaling Peptides and Proteins; Lasers; Locus coeruleus; Locus Coeruleus - metabolism; Locus Coeruleus - pathology; Major depressive disorder; Male; Medical sciences; Medicine; Medicine & Public Health; Mental depression; Microdissection; Middle Aged; Models, Biological; Mood disorders; Nerve Tissue Proteins - genetics; Nerve Tissue Proteins - metabolism; Neuroglia - metabolism; Neurosciences; Neurotransmission; Norepinephrine; Oligonucleotide Array Sequence Analysis - methods; original-article; Pharmacotherapy; Physiological aspects; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk factors; RNA, Messenger - metabolism; Signal transduction; Signal Transduction - physiology; TrkB receptors; Young Adult; United States; Germany; Ann Arbor Michigan; United States--US; California; norepinephrine; laser-capture microdissection; post mortem; microarray; human; monoamine; Mood disorder; Human; Neuroglia; Central nervous system; Postmortem; Monoamine; Depression; Catecholamine; Glutamate; Genetic determinism; Encephalon; Signal transduction; Gene; Laser; Excitatory aminoacid