Usefulness of Serum Cathepsin L as an Independent Biomarker in Patients With Coronary Heart Disease

• Published in: The American journal of cardiology Vol. 103; no. 4; pp. 476 - 481
• Main Authors: Liu, Yingxian, Li, Xiangping, Peng, Daoquan, Tan, Zheng, Liu, Hongmin, Qing, Yingnan, Xue, Yanqiong, Shi, Guo-Ping
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 15.02.2009; Elsevier; Elsevier Limited
• Subjects: Angina, Unstable - blood; Angina, Unstable - diagnostic imaging; Biological and medical sciences; Biomarkers; Biomarkers - blood; Blood Glucose - analysis; C-Reactive Protein - analysis; Cardiology; Cardiology. Vascular system; Cardiovascular; Cardiovascular disease; Case-Control Studies; Cathepsin L; Cathepsins - blood; Cigarettes; Coronary Angiography; Coronary Disease - blood; Coronary Disease - diagnostic imaging; Coronary heart disease; Coronary vessels; Cysteine Endopeptidases - blood; Female; Heart; Humans; Male; Medical imaging; Medical sciences; Middle Aged; Myocardial Infarction - blood; Myocardial Infarction - diagnostic imaging; Smoking; Human; Peptidases; Cathepsin L; Enzyme; Cysteine endopeptidases; Biological marker; Hydrolases; Cardiovascular disease; Serum; Circulatory system; Cardiology; Coronary heart disease

Higher levels of cysteinyl cathepsin L were detected in human atherosclerotic lesions than in healthy aortas. However, a link between human coronary heart disease (CHD) and systemic cathepsin L levels remains unknown. A total of 137 volunteers with diagnosed acute and previous myocardial infarction...