The relationship of hair glucocorticoid levels to immunological and virological outcomes in a large cohort of combination antiretroviral therapy treated people living with HIV

• Published in: BMC infectious diseases Vol. 22; no. 1; pp. 268 - 8
• Main Authors: Zhang, Quan, Li, Xiaoming, Qiao, Shan, Liu, Shuaifeng, Zhou, Yuejiao, Shen, Zhiyong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.03.2022; BioMed Central; BMC
• Subjects: Antiretroviral agents; Antiretroviral drugs; Antiretroviral therapy; Antiretroviral Therapy, Highly Active; Antiviral agents; Body mass index; Care and treatment; CD4 antigen; CD4 count; Chronic illnesses; Complications and side effects; Composition; Corticosteroids; Cortisone; Development and progression; Disease; Dosage and administration; Drug therapy; Enzymes; Ethnicity; Exposure; Glucocorticoids; Glucocorticoids - therapeutic use; Hair; Hair cortisol; Hair cortisone; Health aspects; HIV; HIV (Viruses); HIV Infections; HIV patients; HIV viral load; HIV-1; Hormones; Human immunodeficiency virus; Humans; Hydrocortisone; Immunology; Indicators; Infectious diseases; Lifestyles; Measurement; Medical records; People living with HIV; Questionnaires; Retrospective Studies; Saliva; Sociodemographics; China; Hair cortisone; People living with HIV; CD4 count; Hair cortisol; HIV viral load

Existing literature mostly investigated the relationship of acute or short-term glucocorticoid exposure to HIV disease progression using cortisol levels in serum, saliva, or urine. Data are limited on the relationship of long-term glucocorticoid exposure to HIV disease progression. This study examin...