Modelling trends of CD4 counts for patients on antiretroviral therapy (ART): a comprehensive health care clinic in Nairobi, Kenya

• Published in: BMC infectious diseases Vol. 22; no. 1; p. 29
• Main Authors: Mugo, Caroline W, Shkedy, Ziv, Mwalili, Samuel, Awoke, Tadesse, Braekers, Roel, Wandede, Dolphine, Mwachari, Christina
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.01.2022; BioMed Central; BMC
• Subjects: Anti-HIV Agents - therapeutic use; Antiretroviral agents; Antiretroviral drugs; Antiretroviral Therapy, Highly Active; CD4; CD4 antigen; CD4 Lymphocyte Count; CD4 lymphocytes; Comprehensive Health Care; Drug therapy; Evaluation; Female; Forecasts and trends; Hazard assessment; Health care; Highly active antiretroviral therapy; Highly active antiretroviral therapy(HAART); HIV; HIV Infections - drug therapy; HIV patients; HIV/AIDS; Human immunodeficiency virus; Humans; Immune system; Infectious diseases; Kenya; Medical research; Patient outcomes; Patients; Retrospective Studies; Statistical models; Switches; Teenagers; Trends; Viral Load; Zidovudine; Kenya; Nairobi Kenya; HIV/AIDS; CD4; Highly active antiretroviral therapy(HAART)

In resource-limited settings, changes in CD4 counts constitute an important component in patient monitoring and evaluation of treatment response as these patients do not have access to routine viral load testing. In this study, we quantified trends on CD4 counts in patients on highly active antiretr...