841-P: Scientific Basis for the First-in-Human Trial of “Neo-Islet”–Mediated Functional Cure of T1DM: The Intraperitoneal Administration of “Neo-Islets,” 3-D Organoids of Allogeneic Islet and Mesenchymal Stromal Cells from Rodents, Dogs, and Humans Durably Cures - WESTENFELDER, CHRISTOF; CHOWDHURY, SABIHA S.; GOOCH, ANNA (Diabetes (New York, N.Y.), 2022)
Keywords: Angiogenesis; Apoptosis; Blood glucose; Cell culture; Clinical trials; Diabetes; Diabetes mellitus; Encapsulation; Immune response; Immunomodulation; Immunosuppressive agents; Inflammation; Insulin; Islet cells; Mesenchymal stem cells; Mesenchyme; Omentum; Organoids; Pets; Progenitor cells; Streptozocin; Stromal cells