Association of the European Lactase Persistence Variant (LCT-13910 C>T Polymorphism) with Obesity in the Canary Islands

• Published in: PloS one Vol. 7; no. 8; p. e43978
• Main Authors: Almon, Ricardo, Álvarez-León, Eva Elisa, Serra-Majem, Lluís
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 24.08.2012; Public Library of Science (PLoS)
• Subjects: Adolescent; Adult; Adults; Aged; Alleles; Analysis; Animals; Anthropometry; Biology; Body mass; Body Mass Index; Body size; Body Weight - genetics; Drinking Behavior; Exercise; Female; Genetic aspects; Genetic Association Studies; Genetic polymorphisms; Genetic Predisposition to Disease; Genotype; Genotypes; Humans; Inhabitants; Islands; Lactase; Lactase - genetics; Lactose; Lactose intolerance; Lactose Intolerance - genetics; Male; Medicin; Medicine; Middle Aged; Milk; Mortality; Nutrition; Nutrition surveys; Obesity; Obesity - genetics; Physiological aspects; Polymorphism; Polymorphism, Single Nucleotide; Population studies; Preventive medicine; Regression analysis; Risk factors; Spain; Studies; Surveys; Surveys and Questionnaires; Spain; Canary Islands

European lactose tolerance genotype (LCT -13910 C>T, rs4988234) has been positively associated to body mass indexes (BMI) in a meta-analysis of 31,720 individuals of northern and central European descent. A strong association of lactase persistence (LP) with BMI and obesity has also been traced i...