Pyrethroid resistance in Culex pipiens mosquitoes

• Published in: Pesticide Biochemistry and Physiology Vol. 120; pp. 68 - 76
• Main Authors: Scott, Jeffrey G., Yoshimizu, Melissa Hardstone, Kasai, Shinji
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2015; Elsevier BV
• Subjects: Animals; China; Culex; Culex - drug effects; Culex - genetics; Culex - physiology; Culex pipiens; cytochrome P-450; Cytochrome P450 monooxygenase; environmental factors; Fitness costs; gene overexpression; human diseases; Humans; Insect Vectors; Insecticide Resistance; Insecticide Resistance - genetics; Insecticides; Insecticides - toxicity; Japan; kdr; Knockdown resistance; larvae; Mechanisms of resistance; mutation; Pyrethrins; Pyrethrins - toxicity; Pyrethroid insecticides; resistance mechanisms; Saudi Arabia; Saudi Arabia; China; Japan; Fitness costs; kdr; Pyrethroid insecticides; Cytochrome P450 monooxygenase; Mechanisms of resistance; Knockdown resistance

•Pyrethroid insecticides are frequently used to control Culex pipiens mosquitoes.•High levels of pyrethroid resistance are found in larvae throughout the world.•Multiple Vssc mutations have been found in resistant strains.•Overexpression of CYP9M10 appears to be a mechanism of resistance globally. M...