Comparative Multimodal Meta-analysis of Structural and Functional Brain Abnormalities in Autism Spectrum Disorder and Obsessive-Compulsive Disorder

• Published in: Biological psychiatry (1969) Vol. 82; no. 2; pp. 83 - 102
• Main Authors: Carlisi, Christina O., Norman, Luke J., Lukito, Steve S., Radua, Joaquim, Mataix-Cols, David, Rubia, Katya
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.07.2017
• Subjects: Autism; Autism Spectrum Disorder - diagnostic imaging; Autism Spectrum Disorder - pathology; Autism Spectrum Disorder - physiopathology; Basal Ganglia - diagnostic imaging; Basal Ganglia - pathology; Basal Ganglia - physiopathology; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - pathology; Cerebral Cortex - physiopathology; Cognitive control; Executive Function - physiology; fMRI; Humans; Meta-analysis; Obsessive-Compulsive Disorder - diagnostic imaging; Obsessive-Compulsive Disorder - pathology; Obsessive-Compulsive Disorder - physiopathology; OCD; Psychiatric/Mental Health; VBM; VBM; Autism; fMRI; OCD; Cognitive control; Meta-analysis
• ISSN: 0006-3223; 1873-2402; 1873-2402
• DOI: 10.1016/j.biopsych.2016.10.006

Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) share inhibitory control deficits possibly underlying poor control over stereotyped and repetitive and compulsive behaviors, respectively. However, it is unclear whether these symptom profiles are mediated by common or distinct n...