Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization - Santiago, Helton C.; LeeVan, Elyse; Bennuru, Sasisekhar; Ribeiro-Gomes, Flavia; Mueller, Ellen; Wilson, Mark; Wynn, Thomas; Garboczi, David; Urban, Joseph; Mitre, Edward; Nutman, Thomas B. (Journal of allergy and clinical immunology, 2012)
Keywords: allergens; Allergies; allergy; Allergy and Immunology; Amino Acid Sequence; amino acids; Animals; antibodies; Antibodies - blood; antibody formation; Biological and medical sciences; Blattodea; cockroach; Cockroaches - enzymology; Cockroaches - genetics; Cockroaches - immunology; cross reaction; Cross Reactions; cross-reactivity; Elephantiasis, Filarial - immunology; Epidemiology. Vaccinations; Epitope Mapping; epitopes; Female; filariasis; Fundamental and applied biological sciences. Psychology; Fundamental immunology; General aspects; glutathione; Glutathione Transferase - chemistry; Glutathione Transferase - genetics; Glutathione Transferase - immunology; GST; Heligmosomoides; helminth proteins; Helminth Proteins - chemistry; Helminth Proteins - genetics; Helminth Proteins - immunology; helminths; Helminths - enzymology; Helminths - immunology; Humans; hygiene hypothesis; immunoglobulin E; Immunoglobulin E - blood; Immunoglobulin E - immunology; immunoglobulin G; Immunopathology; Infections; Infectious diseases; Insect Proteins - chemistry; Insect Proteins - genetics; Insect Proteins - immunology; Medical sciences; Mice; Mice, Inbred BALB C; Models, Molecular; molecular mimicry; Molecular Mimicry - immunology; Molecular Sequence Data; Parasites; Parasitic diseases; pathogens; patients; Peptides; Phylogeny; Review boards; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Sequence Analysis, DNA; Trichostrongyloidea - immunology; Trichostrongyloidiasis - immunology; Wuchereria bancrofti; Wuchereria bancrofti - enzymology; Wuchereria bancrofti - genetics; Wuchereria bancrofti - immunology; aa; OR; hygiene hypothesis; DMSO; cockroach; filariasis; Fil; GST; allergy; cross-reactivity; 3-D; HbGST; Ni-A; WbGST; HDM; Fil-A; Bla g 5; 3-Dimensional; Filaria-uninfected; Heligmosomoides bakeri GST-2; Fil − and atopic; Amino acid; Fil + and atopic; Filaria-infected; Glutathione-S transferase