Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS - Prudencio, Mercedes; Belzil, Veronique V; Batra, Ranjan; Ross, Christian A; Gendron, Tania F; Pregent, Luc J; Murray, Melissa E; Overstreet, Karen K; Piazza-Johnston, Amelia E; Desaro, Pamela; Bieniek, Kevin F; DeTure, Michael; et al. (Nature neuroscience, 2015)
Keywords: 38/91; 631/378/1689/1285; 631/378/2583; Adult; Aged; Alternative Splicing; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis - genetics; Analysis; Animal Genetics and Genomics; Behavioral Sciences; Biological Techniques; Biomedicine; C9orf72 Protein; Cerebellum - metabolism; Development and progression; Frontal Lobe - metabolism; Gene expression; Gene Expression Regulation - genetics; Genetic aspects; Genetic Association Studies; Genetic transcription; Health aspects; Heterogeneous-Nuclear Ribonucleoprotein Group F-H - metabolism; Humans; Middle Aged; Mutation; Neurobiology; Neuropathology; Neurosciences; Open reading frames; Physiological aspects; Polyadenylation - genetics; Properties; Proteins; Proteins - genetics; resource; RNA - metabolism; RNA polymerase; RNA splicing; Sequence Analysis, RNA; Transcriptome - genetics; Florida; United States--US; Minnesota