Effective inactivation of Nipah virus in serum samples for safe processing in low-containment laboratories

• Published in: Virology journal Vol. 17; no. 1; p. 151
• Main Authors: Watanabe, Shumpei, Fukushi, Shuetsu, Harada, Toshihiko, Shimojima, Masayuki, Yoshikawa, Tomoki, Kurosu, Takeshi, Kaku, Yoshihiro, Morikawa, Shigeru, Saijo, Masayuki
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.10.2020; BioMed Central; BMC
• Subjects: Aluminum; Aluminum foil; Biosafety; Biosafety level 4; blood serum; Diagnosis; diagnostic techniques; Disease; Disease control; Encephalitis; Epidemics; heat; humans; Infectivity; Laboratories; Lung diseases; Mortality; Nipah henipavirus; Nipah virus; pathogenicity; Respiratory diseases; respiratory tract diseases; Respirovirus; serodiagnosis; Serology; Ultraviolet radiation; Viral diseases; virology; Virus diseases; Virus inactivation; Virus stability; Viruses; Zoonoses; Japan; Malaysia; Singapore; Nipah virus; Biosafety level 4; Diagnosis; Virus inactivation; Virus stability

Nipah virus (NiV) is an emerging zoonotic paramyxovirus that causes severe encephalitis and respiratory disease with a high mortality rate in humans. During large outbreaks of the viral disease, serological testing of serum samples could be a useful diagnostic tool, which could provide information o...