Accuracy of volatile urine biomarkers for the detection and characterization of lung cancer

• Published in: BMC cancer Vol. 15; no. 1; p. 1001
• Main Authors: Mazzone, Peter J., Wang, Xiao-Feng, Lim, Sung, Choi, Humberto, Jett, James, Vachani, Anil, Zhang, Qi, Beukemann, Mary, Seeley, Meredith, Martino, Ray, Rhodes, Paul
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.12.2015; BioMed Central
• Subjects: Adult; Aged; Biological markers; Biomarkers, Tumor - urine; Case-Control Studies; Chemical properties; Colorimetry - methods; Diagnosis; Early Detection of Cancer - methods; Early Detection of Cancer - standards; Female; Humans; Lung cancer; Lung Neoplasms - diagnosis; Lung Neoplasms - urine; Male; Middle Aged; Predictive Value of Tests; Sensitivity and Specificity; Volatile organic compounds; Volatile Organic Compounds - urine

The mixture of volatile organic compounds in the headspace gas of urine may be able to distinguish lung cancer patients from relevant control populations. Subjects with biopsy confirmed untreated lung cancer, and others at risk for developing lung cancer, provided a urine sample. A colorimetric sens...