Safety and immunogenicity of a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125) in healthy young adults - Treanor, John J.; Taylor, David N.; Tussey, Lynda; Hay, Christine; Nolan, Carrie; Fitzgerald, Theresa; Liu, Ge; Kavita, Uma; Song, Langzhou; Dark, Irving; Shaw, Alan (Vaccine, 2010)
Keywords: Adolescent; Adult; Allergy and Immunology; Antibodies, Bacterial - blood; Antibodies, Viral - blood; Antibody response; Applied microbiology; Biological and medical sciences; C-reactive protein; C-Reactive Protein - analysis; Cell culture; Clinical trials; Cytokines; Cytokines - blood; E coli; Escherichia coli; Escherichia coli - genetics; Fatigue; Female; Flagellin; Flagellin - genetics; Flagellin - immunology; Fundamental and applied biological sciences. Psychology; Gene Expression; Headache; Hemagglutination Inhibition Tests; Hemagglutinins; Hemagglutinins, Viral - genetics; Hemagglutinins, Viral - immunology; Humans; Immune response; Immunogenicity; Influenza; Influenza Vaccines - administration & dosage; Influenza Vaccines - adverse effects; Influenza Vaccines - genetics; Influenza Vaccines - immunology; Influenza virus; Injections, Intramuscular; Islands; Ligands; Male; Manganese; Microbiology; Middle Aged; Neutralization Tests; Pain; Pandemics; Placebos - administration & dosage; TLR5 protein; Toll-like receptors; Vaccination; Vaccination - methods; Vaccine; Vaccines; Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects); Vaccines, Synthetic - administration & dosage; Vaccines, Synthetic - adverse effects; Vaccines, Synthetic - genetics; Vaccines, Synthetic - immunology; Virions; Viruses; Young Adult; Young adults; Clinical trials; Influenza; Vaccine; Infection; Immunogenicity; Hemagglutinin; Viral disease; Flagellin; Clinical trial; Influenza A