Circulating brain-enriched microRNAs as novel biomarkers for detection and differentiation of neurodegenerative diseases

• Published in: Alzheimer's research & therapy Vol. 9; no. 1; pp. 89 - 13
• Main Authors: Sheinerman, Kira S., Toledo, Jon B., Tsivinsky, Vladimir G., Irwin, David, Grossman, Murray, Weintraub, Daniel, Hurtig, Howard I., Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo F., Elman, Lauren B., Trojanowski, John Q., Umansky, Samuil R.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.11.2017; BioMed Central; BMC
• Subjects: Alzheimer’s disease; Amyotrophic lateral sclerosis; Blood-based biomarkers; Degeneration; Frontotemporal dementia; MicroRNA; Nervous system; Parkinson’s disease; Amyotrophic lateral sclerosis; microRNA; Alzheimer’s disease; Blood-based biomarkers; Frontotemporal dementia; Parkinson’s disease

Minimally invasive specific biomarkers of neurodegenerative diseases (NDs) would facilitate patient selection and disease progression monitoring. We describe the assessment of circulating brain-enriched microRNAs as potential biomarkers for Alzheimer's disease (AD), frontotemporal dementia (FTD...