Exosome-derived noncoding RNAs in gastric cancer: functions and clinical applications

• Published in: Molecular cancer Vol. 20; no. 1; pp. 99 - 15
• Main Authors: Tang, Xiao-Huan, Guo, Ting, Gao, Xiang-Yu, Wu, Xiao-Long, Xing, Xiao-Fang, Ji, Jia-Fu, Li, Zi-Yu
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 30.07.2021; BioMed Central; BMC
• Subjects: Animals; Antigens; B cells; Biomarker; Biomarkers, Tumor; Body fluids; Cancer; Cell interactions; Development and progression; Disease Progression; Disease Susceptibility; Drug resistance; Drug Resistance, Neoplasm - genetics; Epithelial-Mesenchymal Transition; Exosome; Exosomes; Exosomes - metabolism; Gastric cancer; Gene Expression Regulation, Neoplastic; Guanylate cyclase; Health aspects; Helicobacter Infections - complications; Helicobacter Infections - microbiology; Humans; Infections; Medical prognosis; Metastasis; Microenvironments; MicroRNAs; Molecular Targeted Therapy; ncRNA; Neoplasm Metastasis; Neoplasm Staging; Plasma; Prognosis; Progression; Proteins; Review; RNA, Untranslated - genetics; RNA, Untranslated - metabolism; Stomach cancer; Stomach Neoplasms - etiology; Stomach Neoplasms - metabolism; Stomach Neoplasms - pathology; Stomach Neoplasms - therapy; Tumor Escape - genetics; Tumor Escape - immunology; Tumor Microenvironment; Tumorigenesis; Tumors; Progression; Biomarker; ncRNA; Exosome; Gastric cancer

Exosomes are a subpopulation of the tumour microenvironment (TME) that transmit various biological molecules to promote intercellular communication. Exosomes are derived from nearly all types of cells and exist in all body fluids. Noncoding RNAs (ncRNAs) are among the most abundant contents in exoso...