CTLA4-Ig treatment induces M1–M2 shift in cultured monocyte-derived macrophages from healthy subjects and rheumatoid arthritis patients - Cutolo, Maurizio; Soldano, Stefano; Gotelli, Emanuele; Montagna, Paola; Campitiello, Rosanna; Paolino, Sabrina; Pizzorni, Carmen; Sulli, Alberto; Smith, Vanessa; Tardito, Samuele (Arthritis research & therapy, 2021)
Keywords: Abatacept; Abatacept - metabolism; Abatacept - pharmacology; Abatacept - therapeutic use; Antigens; Arthritis; Arthritis, Rheumatoid - drug therapy; Arthritis, Rheumatoid - metabolism; Care and treatment; Cells, Cultured; CTLA-4 Antigen; CTLA4-Ig; Cytokines; Diagnosis; Dosage and administration; Drug dosages; Gene expression; Genotype & phenotype; Health aspects; Healthy Volunteers; Humans; Inflammation; Kinases; Leukocytes, Mononuclear; M1–M2 polarisation; Macrophages; Macrophages - metabolism; Monocytes; Nonsteroidal anti-inflammatory drugs; Physiological aspects; Polymerase chain reaction; Proteins; Rheumatoid arthritis; Rheumatology; Italy; Germany; Monocytes; Abatacept; M1–M2 polarisation; Rheumatoid arthritis; Autoimmune; CTLA4-Ig; Macrophages