Mortality Results from a Randomized Prostate-Cancer Screening Trial

• Published in: The New England journal of medicine Vol. 360; no. 13; pp. 1310 - 1319
• Main Authors: Andriole, Gerald L, Crawford, E. David, Grubb, Robert L, Buys, Saundra S, Chia, David, Church, Timothy R, Fouad, Mona N, Gelmann, Edward P, Kvale, Paul A, Reding, Douglas J, Weissfeld, Joel L, Yokochi, Lance A, O'Brien, Barbara, Clapp, Jonathan D, Rathmell, Joshua M, Riley, Thomas L, Hayes, Richard B, Kramer, Barnett S, Izmirlian, Grant, Miller, Anthony B, Pinsky, Paul F, Prorok, Philip C, Gohagan, John K, Berg, Christine D
• Format: Journal Article
• Language: English
• Published: Waltham, MA Massachusetts Medical Society 26.03.2009
• Subjects: Age; Aged; Biological and medical sciences; Digital Rectal Examination - adverse effects; Epidemiology; Follow-Up Studies; General aspects; Humans; Incidence; Male; Mass Screening - adverse effects; Medical sciences; Medical screening; Men; Middle Aged; Mortality; Patient Compliance; Prostate cancer; Prostate-Specific Antigen - blood; Prostatic Neoplasms - diagnosis; Prostatic Neoplasms - epidemiology; Prostatic Neoplasms - mortality; Public health. Hygiene; Public health. Hygiene-occupational medicine; United States - epidemiology; United States; United States > US; Urinary system disease; Prostate disease; Mortality; Malignant tumor; Medical screening; Epidemiology; Result; Medicine; Randomization; Clinical trial; Male genital diseases; Prostate cancer; Cancer

In this study involving nearly 77,000 men, investigators analyzed the effect of screening with prostate-specific–antigen testing and digital rectal examination on the rate of death from prostate cancer, as compared with usual care. After a follow-up of 7 years, the death rates from prostate cancer d...