Notch4 mediates vascular remodeling via ERK/JNK/P38 MAPK signaling pathways in hypoxic pulmonary hypertension - Guo, Mingzhou; Zhang, Mengzhe; Cao, Xiaopei; Fang, Xiaoyu; Li, Ke; Qin, Lu; He, Yuanzhou; Zhao, Jianping; Xu, Yongjian; Liu, Xiansheng; Li, Xiaochen (Respiratory research, 2022)
Keywords: Antibodies; Apoptosis; Blood pressure; Care and treatment; Cell adhesion & migration; Cell cycle; Cell growth; Cell migration; Cell proliferation; Cell surface; Cell viability; Chronic obstructive pulmonary disease; Diagnosis; Extracellular signal-regulated kinase; Health aspects; Heart; Human pulmonary arterial smooth muscle cells; Hypertension; Hypertrophy; Hypoxia; Hypoxic pulmonary hypertension; Immunoprecipitation; Kinases; Lung diseases; Lungs; MAP kinase; Medical prognosis; Membrane proteins; Mitogen-activated protein kinase; mRNA; Muscles; Notch4; Phosphorylation; Proteins; Pulmonary arteries; Pulmonary artery; Pulmonary hypertension; Reagents; RNA-mediated interference; Signal transduction; Signaling; siRNA; Smooth muscle; Systolic pressure; Therapeutic targets; Ventricle; Western blotting; China; United States--US; Japan; Notch4; Mitogen-activated protein kinase; Human pulmonary arterial smooth muscle cells; Hypoxic pulmonary hypertension