Sniffer dogs can identify lung cancer patients from breath and urine samples

• Published in: BMC cancer Vol. 21; no. 1; pp. 917 - 12
• Main Authors: Feil, Charlotte, Staib, Frank, Berger, Martin R., Stein, Thorsten, Schmidtmann, Irene, Forster, Andreas, Schimanski, Carl C.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.08.2021; BioMed Central; BMC
• Subjects: Age; Animals; Auscultation; Biological markers; Biomarkers; Biopsy; Bronchoscopes; Bronchoscopy; Cancer; Cancer patients; Clinical trials; Detection dogs; Diagnosis; Dogs; Early Detection of Cancer; Exhalation; Hospitals; Humans; Lung cancer; Lung Neoplasms - diagnosis; Lung Neoplasms - metabolism; Mortality; Olfactory detection; Olfactory Perception; Oncology, Experimental; Organic compounds; Patients; Physiological aspects; Respiratory Function Tests; Sensitivity and Specificity; Testing; Tomography, X-Ray Computed; Tumors; Urine; VOCs; Volatile organic compounds; Volatile Organic Compounds - metabolism; Volatile Organic Compounds - urine; Working Dogs - physiology; Germany; Volatile organic compounds; Olfactory detection; Lung cancer

Lung cancer is the most common oncological cause of death in the Western world. Early diagnosis is critical for successful treatment. However, no effective screening methods exist. A promising approach could be the use of volatile organic compounds as diagnostic biomarkers. To date there are several...