Trends in the epidemiology of young-onset colorectal cancer: a worldwide systematic review

• Published in: BMC cancer Vol. 20; no. 1; pp. 288 - 14
• Main Authors: Saad El Din, Khalid, Loree, Jonathan M., Sayre, Eric C., Gill, Sharlene, Brown, Carl J., Dau, Hallie, De Vera, Mary A.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.04.2020; BioMed Central; BMC
• Subjects: Adenomatous polyposis coli; Adult; Africa - epidemiology; Age; Age of Onset; Analysis; Annual reports; Asia - epidemiology; Australia - epidemiology; Cancer; Cancer research; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - diagnosis; Colorectal Neoplasms - epidemiology; Confidence intervals; Databases, Factual - statistics & numerical data; Epidemiology; Estimates; Europe - epidemiology; Global Burden of Disease - trends; Humans; Incidence; Meta-analysis; Middle Aged; North America - epidemiology; Oceania - epidemiology; Population studies; Prevalence; Prevalence studies (Epidemiology); Quality; Rectum; Reviews; Studies; Subject heading schemes; Systematic review; Trends; Young Adult; Young-adult cancer; Australia; Asia; North America; Europe; Africa; Oceania; Canada; United States > US; Epidemiology; Cancer; Incidence; Meta-analysis; Young-adult cancer

Recent data suggest that the risk of young-onset colorectal cancer (yCRC), in adults less than 50 years of age, is increasing. To confirm findings and identify contemporary trends worldwide, we conducted a systematic review of studies examining population-level trends in yCRC epidemiology. We search...