The blood level of thioredoxin 1 as a supporting biomarker in the detection of breast cancer

• Published in: BMC cancer Vol. 22; no. 1; pp. 12 - 14
• Main Authors: Lee, Youn Ju, Kim, Young, Choi, Bo Bae, Kim, Je Ryong, Ko, Hye Mi, Suh, Kyoung Hoon, Lee, Jin Sun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.01.2022; BioMed Central; BMC
• Subjects: Adult; Aged; Aged, 80 and over; Biomarkers; Biomarkers, Tumor - blood; Biopsy; Blood; Breast Cancer; Breast Neoplasms - diagnosis; Cervix; Cross-Sectional Studies; Developing countries; Diagnosis; Diagnostics; Early Detection of Cancer - methods; Female; Genetic aspects; Health aspects; Humans; LDCs; Mammography; Middle Aged; Monoclonal antibodies; Mortality; Neoplasm Staging - methods; Patients; Reproducibility of Results; Retrospective Studies; ROC Curve; Sensitivity; Sensitivity and Specificity; Specificity; Thioredoxin; Thioredoxin 1; Thioredoxins - blood; Thyroid cancer; South Korea; Biomarker; Early diagnosis; Sensitivity; Specificity; Thioredoxin 1; Diagnostics; Mammography; Breast Cancer; Diagnostic interval; Blood

There is a long-time unmet need for a means to detect breast cancer (BC) using blood. Although mammography is accepted as the gold standard for screening, a blood-based diagnostic can complement mammography and assist in the accurate detection of BC in the diagnostic process period of early diagnosi...