Sickle cell disease induces resistance to cutaneous carcinogenesis

• Published in: Orphanet journal of rare diseases Vol. 15; no. 1; pp. 66 - 5
• Main Authors: Soutou, Boutros, Senet, Patricia, Lionnet, François, Habibi, Anoosha, Aractingi, Sélim
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.03.2020; BioMed Central; BMC
• Subjects: Actinic keratosis; Age; Cancer; Carcinogenesis; Carcinoma; Care and treatment; Dermatology; Disease resistance; Diseases; Drug dosages; Hematology; Hemoglobin; Human health and pathology; Hydroxyurea; Keratosis; Leg ulcers; Life Sciences; Medical prognosis; Medical research; Melanoma; Mutation; Rare diseases; Santé publique et épidémiologie; Sickle cell anemia; Sickle cell disease; Skin; Skin cancer; Skin diseases; Skin ulcer; Tumors; Ulcers; France; Sub-Saharan Africa; Africa; West Indies; Hydroxyurea; Sickle cell disease; Skin ulcer; Skin cancer

While skin carcinomas are reported in chronic ulcers and in patients treated with hydroxyurea (HU) for myeloproliferative neoplasms, no skin carcinoma has been reported in patients with sickle cell disease (SCD), presenting chronic skin ulcers or treated with HU. The objective was to estimate the ri...