Kinetics of SARS-CoV-2 specific IgM and IgG responses in COVID-19 patients

• Published in: Emerging microbes & infections Vol. 9; no. 1; pp. 940 - 948
• Main Authors: Sun, Baoqing, Feng, Ying, Mo, Xiaoneng, Zheng, Peiyan, Wang, Qian, Li, Pingchao, Peng, Ping, Liu, Xiaoqing, Chen, Zhilong, Huang, Huimin, Zhang, Fan, Luo, Wenting, Niu, Xuefeng, Hu, Peiyu, Wang, Longyu, Peng, Hui, Huang, Zhifeng, Feng, Liqiang, Li, Feng, Zhang, Fuchun, Li, Fang, Zhong, Nanshan, Chen, Ling
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2020; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Aged; Antibodies, Viral - blood; Antibodies, Viral - immunology; Betacoronavirus - immunology; C-reactive protein; C-Reactive Protein - analysis; C-Reactive Protein - immunology; Clinical Laboratory Techniques; Coronavirus Infections - blood; Coronavirus Infections - diagnosis; Coronavirus Infections - immunology; Coronavirus Nucleocapsid Proteins; Coronaviruses; COVID-19; COVID-19 Testing; Critical Care - statistics & numerical data; Female; Humans; IgG; IgM; Immunoglobulin G - blood; Immunoglobulin G - immunology; Immunoglobulin M - blood; Immunoglobulin M - immunology; Kinetics; Male; Middle Aged; Nucleocapsid Proteins - blood; Nucleocapsid Proteins - immunology; Pandemics; Phosphoproteins; Pneumonia, Viral - blood; Pneumonia, Viral - diagnosis; Pneumonia, Viral - immunology; Proteins; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus - blood; Spike Glycoprotein, Coronavirus - immunology; COVID-19; IgG; SARS-CoV-2; C-reactive protein; IgM

The emerging COVID-19 caused by SARS-CoV-2 infection poses severe challenges to global public health. Serum antibody testing is becoming one of the critical methods for the diagnosis of COVID-19 patients. We investigated IgM and IgG responses against SARS-CoV-2 nucleocapsid (N) and spike (S) protein...