Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

• Published in: Emerging microbes & infections Vol. 9; no. 1; pp. 1123 - 1130
• Main Authors: Han, Huan, Ma, Qingfeng, Li, Cong, Liu, Rui, Zhao, Li, Wang, Wei, Zhang, Pingan, Liu, Xinghui, Gao, Guosheng, Liu, Fang, Jiang, Yingan, Cheng, Xiaoming, Zhu, Chengliang, Xia, Yuchen
• Format: Journal Article
• Language: English
• Published: United States Taylor & Francis 01.01.2020; Taylor & Francis Ltd; Taylor & Francis Group
• Subjects: Betacoronavirus; Biomarkers - blood; C-Reactive Protein - analysis; China; Coronavirus Infections - diagnosis; Coronavirus Infections - immunology; Coronavirus Infections - physiopathology; Coronaviruses; COVID-19; Critical Illness; Cytokine Release Syndrome - immunology; Cytokine Release Syndrome - virology; Cytokine storm; Cytokines - blood; Humans; inflammatory cytokines; Interleukin 10; Interleukin 6; Interleukin-10 - blood; Interleukin-6 - blood; Pandemics; Pneumonia, Viral - diagnosis; Pneumonia, Viral - immunology; Pneumonia, Viral - physiopathology; Respiratory failure; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; China; COVID-19; Interleukin 6; SARS-CoV-2; cytokine storm; inflammatory cytokines; Interleukin 10

Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly spread across many other countries. While the majority of patients were considered mild, critically ill patients involving respiratory failure and multiple organ dysfunction syndrome are not uncommon, which cou...