LINC00958 promotes bladder cancer carcinogenesis by targeting miR-490-3p and AURKA

• Published in: BMC cancer Vol. 21; no. 1; pp. 1145 - 14
• Main Authors: Zhen, Hongtao, Du, Peng, Yi, Qiang, Tang, Xiaolong, Wang, Tongqing
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 26.10.2021; BioMed Central; BMC
• Subjects: Apoptosis; AURKA; Aurora Kinase A - genetics; Aurora Kinase A - metabolism; Binding sites; Bladder cancer; Cancer; Carcinogenesis; Cell cycle; Cell growth; Cell proliferation; Development and progression; Female; Genetic aspects; Health aspects; Humans; Kinases; LINC00958; Localization; Male; Malignancy; Membranes; MicroRNAs - genetics; MicroRNAs - metabolism; Middle Aged; miR-490-3p; Protein kinases; RNA; RNA, Long Noncoding - genetics; RNA, Long Noncoding - metabolism; Tumor cell lines; Tumorigenesis; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - metabolism; Urinary Bladder Neoplasms - pathology; China; United States > US; miR-490-3p; Bladder cancer; LINC00958; AURKA

Bladder cancer is a prevalent malignancy of the urinary system, in which long non-coding RNAs (lncRNAs) are highly associated. We aimed to elucidate the role of LINC00958 in bladder cancer. LINC00958 expression levels were measured using qRT-PCR. The interaction of LINC00958-miR-490-3p-AURKA was ana...