Prognostic value of platelet recovery degree before and after achieving minimal residual disease negative complete remission in acute myeloid leukemia patients

• Published in: BMC cancer Vol. 20; no. 1; pp. 732 - 8
• Main Authors: Wang, Yang, Wang, Hua, Wang, Weida, Liu, Wenjian, Liu, Nawei, Liu, Shuang, Lu, Yue
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 05.08.2020; BioMed Central; BMC
• Subjects: Acute myelocytic leukemia; Acute myeloid leukemia; Acute myeloid leukemia (AML); Adolescent; Adult; Aged; Analysis; Blood Platelets; Bone marrow; Bone Marrow - drug effects; Care and treatment; Chemotherapy; Child; Child, Preschool; Complete remission (CR); Confidence intervals; Cytogenetics; Female; Humans; Leukemia; Leukemia, Myeloid, Acute - blood; Leukemia, Myeloid, Acute - drug therapy; Leukemia, Myeloid, Acute - mortality; Male; Medical prognosis; Middle Aged; Minimal residual disease; Multivariate Analysis; Myeloid leukemia; Neoplasm, Residual; Overall survival (OS); Patient outcomes; Patients; Platelet Count; Platelet recovery degree; Platelets; Prognosis; Progression free survival (PFS); Progression-Free Survival; Remission; Remission Induction; Retrospective Studies; Software; Survival analysis; Young Adult; Progression free survival (PFS); Overall survival (OS); Complete remission (CR); Platelet recovery degree; Acute myeloid leukemia (AML)

Risk stratification and prognosis prediction of acute myeloid leukemia (AML) are largely dependent on pre-treatment information. However, post-treatment data also provides much useful information. In this retrospective study, we explored whether the level of blood count recovery before and after the...