Fatal deep venous thrombosis and pulmonary embolism secondary to melioidosis in China: case report and literature review

• Published in: BMC infectious diseases Vol. 19; no. 1; pp. 984 - 6
• Main Authors: Wu, Hua, Huang, Dongliang, Wu, Biao, Pan, Mengjie, Lu, Binghuai
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.11.2019; BioMed Central; BMC
• Subjects: Anti-Bacterial Agents - administration & dosage; Antibacterial agents; Antibiotics; Anticoagulants; Antimicrobial agents; Bacterial infections; Bone marrow; Burkholderia pseudomallei; Burkholderia pseudomallei - classification; Burkholderia pseudomallei - drug effects; Burkholderia pseudomallei - genetics; Burkholderia pseudomallei - isolation & purification; Case Report; Case reports; Cefoperazone; China; Construction industry; Construction workers; Deep venous thrombosis; Diabetes; Diabetes mellitus; Diagnosis; Embolism; Embolisms; Farmers; Fatal Outcome; Fatalities; Fever; Genomes; Health aspects; Health risks; Heparin; Heparin - administration & dosage; Hepatitis; Humans; Imipenem; Infection; Infections; Infectious diseases; Levofloxacin; Literature reviews; Male; Melioidosis; Melioidosis - complications; Melioidosis - microbiology; Middle Aged; Mortality; Pathogens; Pseudomonas infections; Pulmonary arteries; Pulmonary embolism; Pulmonary Embolism - drug therapy; Pulmonary Embolism - etiology; Pulmonary embolisms; Risk factors; Sepsis; Soil contamination; Sputum; Tazobactam; Therapeutic applications; Thigh; Thromboembolism; Thrombophlebitis; Thrombosis; Tightness; Tuberculosis; Veins & arteries; Venous Thrombosis - drug therapy; Venous Thrombosis - etiology; Workers; China; Melioidosis; Pulmonary embolism; Burkholderia pseudomallei; Deep venous thrombosis

Burkholderia pseudomallei is a gram-negative bacterium and the causative pathogen of melioidosis, which manifests a variety ranges of infection symptoms. However, deep venous thrombosis (DVT) and pulmonary embolism (PE) secondary to bacteremic melioidosis are rarely documented in the literature. Her...