Sentinel lymph node procedure in patients with recurrent vulvar squamous cell carcinoma: a proposed protocol for a multicentre observational study

• Published in: BMC cancer Vol. 22; no. 1; p. 445
• Main Authors: van Doorn, Helena C, Oonk, Maaike H M, Fons, Guus, Gaarenstroom, Katja N, de Hullu, Joanne, van Rosmalen, Joost, van Beekhuizen, Heleen J
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23.04.2022; BioMed Central; BMC
• Subjects: Cancer; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - surgery; Care and treatment; Complications; Consent; Edema; Female; Genital cancers; Humans; Lymph Node Excision; Lymph nodes; Lymph Nodes - pathology; Lymphadenopathy - pathology; Lymphatic drainage; Lymphatic Metastasis - pathology; Lymphatic system; Medical imaging; Metastasis; Methods; Multicenter Studies as Topic; Neoplasm Recurrence, Local - pathology; Neoplasm Recurrence, Local - surgery; Observational studies; Observational Studies as Topic; Oncology, Experimental; Patients; Prospective Studies; Quality of Life; Questionnaires; Radiation therapy; Recurrence; Relapse; Sentinel lymph node; Sentinel Lymph Node - pathology; Sentinel Lymph Node - surgery; Sentinel lymph node biopsy; Sentinel Lymph Node Biopsy - methods; Squamous cell carcinoma; Statistical analysis; Study Protocol; Surgery; Surgical drains; Surgical outcomes; Tumors; Vulvar cancer; Vulvar Neoplasms - pathology; Vulvar Neoplasms - surgery; Wound drainage; Netherlands; Recurrence; Sentinel lymph node; Vulvar cancer

Standard groin treatment in recurrent vulvar cancer consists of uni- or bilateral inguinofemoral lymphadenectomy (IFL), whereas in the primary setting women with selected unifocal tumours will undergo a sentinel lymph node (SLN) procedure. The SLN procedure results in fewer short and long-term seque...