Identification of a pyroptosis-related prognostic signature in breast cancer

• Published in: BMC cancer Vol. 22; no. 1; pp. 429 - 16
• Main Authors: Chen, Hanghang, Luo, Haihua, Wang, Jieyan, Li, Jinming, Jiang, Yong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.04.2022; BioMed Central; BMC
• Subjects: Analysis; Atrophy; Biomarkers, Tumor - genetics; Breast Cancer; Breast Neoplasms - genetics; Cancer; Cancer therapies; Care and treatment; Cell death; Chemotherapy; Diagnosis; Female; Females; Gene expression; Gene set enrichment analysis; Genes; Genetic aspects; Genomes; Health aspects; Humans; Medical prognosis; Metastases; Microenvironments; Performance evaluation; Prognosis; Pyroptosis; Pyroptosis - genetics; Risk factors; Risk groups; RNA sequencing; Tumor immune microenvironment; Tumor Microenvironment - genetics; Tumor mutational burden; Tumorigenesis; Tumors; Taiwan; Tumor mutational burden; Tumor immune microenvironment; Prognosis; Pyroptosis; Breast Cancer

The relationship between pyroptosis and cancer is complex. It is controversial that whether pyroptosis represses or promotes tumor development. This study aimed to explore prognostic molecular characteristics to predict the prognosis of breast cancer (BRCA) based on a comprehensive analysis of pyrop...