mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant - Edara, Venkata-Viswanadh; Manning, Kelly E.; Ellis, Madison; Lai, Lilin; Moore, Kathryn M.; Foster, Stephanie L.; Floyd, Katharine; Davis-Gardner, Meredith E.; Mantus, Grace; Nyhoff, Lindsay E.; Bechnak, Sarah; Alaaeddine, Ghina; et al. (Cell reports. Medicine, 2022)
Keywords: 2019-nCoV Vaccine mRNA-1273 - immunology; Adult; Advanced Basic Science; Aged; Animals; Antibodies, Neutralizing - blood; Antibodies, Neutralizing - immunology; Antibodies, Viral - blood; Antibodies, Viral - immunology; antibody; B.1.1.529; BNT162 Vaccine - immunology; booster dose; Chlorocebus aethiops; Cohort Studies; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 - virology; Female; Humans; Immunization, Secondary - methods; live-virus; Male; Middle Aged; mRNA vaccines; Mutation; neutralization assay; Neutralization Tests; Omicron; Omicron variant; SARS-CoV-2; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Vaccination - methods; vaccine induced immunity; Vero Cells; Young Adult; Omicron variant; SARS-CoV-2; antibody; B.1.1.529; booster dose; mRNA vaccines; neutralization assay; live-virus; Omicron; vaccine induced immunity