Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites

• Published in: eLife Vol. 4; p. e06974
• Main Authors: Woo, Yong H, Ansari, Hifzur, Otto, Thomas D, Klinger, Christen M, Kolisko, Martin, Michálek, Jan, Saxena, Alka, Shanmugam, Dhanasekaran, Tayyrov, Annageldi, Veluchamy, Alaguraj, Ali, Shahjahan, Bernal, Axel, del Campo, Javier, Cihlář, Jaromír, Flegontov, Pavel, Gornik, Sebastian G, Hajdušková, Eva, Horák, Aleš, Janouškovec, Jan, Katris, Nicholas J, Mast, Fred D, Miranda-Saavedra, Diego, Mourier, Tobias, Naeem, Raeece, Nair, Mridul, Panigrahi, Aswini K, Rawlings, Neil D, Padron-Regalado, Eriko, Ramaprasad, Abhinay, Samad, Nadira, Tomčala, Aleš, Wilkes, Jon, Neafsey, Daniel E, Doerig, Christian, Bowler, Chris, Keeling, Patrick J, Roos, David S, Dacks, Joel B, Templeton, Thomas J, Waller, Ross F, Lukeš, Julius, Oborník, Miroslav, Pain, Arnab
• Format: Journal Article
• Language: English
• Published: England eLife Sciences Publications Ltd 15.07.2015; eLife Sciences Publications, Ltd
• Subjects: Algae; Alveolata - genetics; Apicomplexa; Biology; Chromera velia; College campuses; Deoxyribonucleic acid; DNA; DNA, Algal - chemistry; DNA, Algal - genetics; Environmental conditions; evolution of parasitism; Evolution, Molecular; Flagella; Gene expression; Gene Expression Profiling; Genes; Genomes; Genomics; Genomics and Evolutionary Biology; Intracellular; Laboratories; malaria; Metabolic pathways; Microbiology and Infectious Disease; Molecular Sequence Data; Parasites; Parasitism; Parasitology; Phylogenetics; Plasmodium; Protein families; Reptiles & amphibians; Ribonucleic acid; RNA; RNA-binding protein; Science; Sequence Analysis, DNA; toxoplasmosis; Vitrella brassicaformis; Chromera velia; evolutionary biology; infectious disease; toxoplasmosis; evolution of parasitism; Vitrella brassicaformis; microbiology; genomics; malaria

The eukaryotic phylum Apicomplexa encompasses thousands of obligate intracellular parasites of humans and animals with immense socio-economic and health impacts. We sequenced nuclear genomes of Chromera velia and Vitrella brassicaformis, free-living non-parasitic photosynthetic algae closely related...