Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI - Feis, Rogier A.; Bouts, Mark J.R.J.; Panman, Jessica L.; Jiskoot, Lize C.; Dopper, Elise G.P.; Schouten, Tijn M.; de Vos, Frank; van der Grond, Jeroen; van Swieten, John C.; Rombouts, Serge A.R.B. (NeuroImage clinical, 2018)
Keywords: Adult; Asymptomatic Diseases - classification; C9orf72, human; classification; Diffusion Tensor Imaging; Diffusion Tensor Imaging - classification; Diffusion Tensor Imaging - methods; Female; Frontotemporal dementia; Frontotemporal Dementia - classification; Frontotemporal Dementia - diagnostic imaging; Frontotemporal Dementia - genetics; GRN protein, human; Heterozygote; Humans; machine learning; Magnetic Resonance Imaging - classification; Magnetic Resonance Imaging - methods; Male; MAPT protein, human; Middle Aged; Multimodal Imaging - classification; Multimodal Imaging - methods; Multimodal MRI; Mutation - genetics; Radiology; Regular; Resting-state functional MRI; Retrospective Studies; FCor; MAPT protein, human; GRN; 3DT1w; AxD; AUC; Pcor; MMSE; WM; DWI; MD; Multimodal MRI; GMD; (rs-f)MRI; GRN protein, human; GM; ICA; ROC; TBSS; classification; machine learning; Diffusion Tensor Imaging; (bv)FTD; WMD; RD; C9orf72, human; DTI; Resting-state functional MRI; FA; MAPT; Frontotemporal dementia; C9orf72; Radial diffusivity; Area under the receiver operating characteristics curve; Progranulin; Sparse L1-regularised partial correlations; White matter; Axial diffusivity; Fractional anisotropy; Chromosome 9 open reading frame 72; Full correlations; Receiver operating characteristics; Grey matter density; (resting-state functional) Magnetic resonance imaging; Diffusion-weighted imaging; Mean diffusivity; (behavioural variant) Frontotemporal dementia; 3DT 1w; 3-dimensional T 1-weighted; Microtubule-associated protein Tau; White matter density; Mini-mental state examination; Tract-based spatial statistics; Grey matter; Independent component analysis; ROC, Receiver operating characteristics; 3DT1w, 3-dimensional T1-weighted; FA, Fractional anisotropy; GM, Grey matter; GRN, Progranulin; ICA, Independent component analysis; DTI, Diffusion tensor imaging; MD, Mean diffusivity; DWI, Diffusion-weighted imaging; FCor, Full correlations; (bv)FTD, (behavioural variant) Frontotemporal dementia; WMD, White matter density; GMD, Grey matter density; MAPT, Microtubule-associated protein Tau; TBSS, Tract-based spatial statistics; WM, White matter