Three-dimensional studies of Prop1-expressing cells in the rat pituitary just before birth

• Published in: Cell and tissue research Vol. 354; no. 3; pp. 837 - 847
• Main Authors: Yako, Hideji, Kato, Takako, Yoshida, Saishu, Higuchi, Masashi, Chen, Mo, Kanno, Naoko, Ueharu, Hiroki, Kato, Yukio
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.12.2013; Springer Berlin Heidelberg; Springer; Springer Nature B.V
• Subjects: Animals; Biomedical and Life Sciences; Biomedicine; biosynthesis; Birth; Cell Differentiation; Cell Differentiation - physiology; Cell Growth Processes; Cell Growth Processes - physiology; Cellular biology; cytology; embryology; Female; Gene expression; genetics; Homeodomain Proteins; Homeodomain Proteins - biosynthesis; Homeodomain Proteins - genetics; Homeodomain Proteins - metabolism; Human Genetics; metabolism; Molecular Medicine; parenchyma; physiology; Pituitary Gland; Pituitary Gland - cytology; Pituitary Gland - embryology; Pituitary Gland - metabolism; Pregnancy; Proteomics; Rats; Rats, Wistar; Regular Article; Rodents; SOXB1 Transcription Factors; SOXB1 Transcription Factors - biosynthesis; SOXB1 Transcription Factors - genetics; SOXB1 Transcription Factors - metabolism; Stem cells; Stem Cells - cytology; Stem Cells - metabolism; transcription factors; Transcription Factors - biosynthesis; Transcription Factors - genetics; Transcription Factors - metabolism; PROP1; Rathke’s pouch; Pituitary; Stem cell; PRX; Progenitor cell

Recently, we demonstrated that differentiation was underway as early as embryonic day (E) 13.5 in the lateral region of the rat pituitary primordium. In this study, we analyze the heterogeneous property of cells in the pituitary at E21.5 (just before birth) leading to its biological function with th...