The relationship between autophagy and the immune system and its applications for tumor immunotherapy

• Published in: Molecular cancer Vol. 18; no. 1; pp. 17 - 22
• Main Authors: Jiang, Guan-Min, Tan, Yuan, Wang, Hao, Peng, Liang, Chen, Hong-Tao, Meng, Xiao-Jun, Li, Ling-Ling, Liu, Yan, Li, Wen-Fang, Shan, Hong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 24.01.2019; BioMed Central; BMC
• Subjects: Animals; Antigen presentation; Antigens; Apoptosis; Autophagy; Autophagy - immunology; B cells; Cancer therapies; Cell cycle; Cell growth; Colorectal cancer; Cytokines; Cytokines - immunology; Cytotoxicity; Development and progression; Drug therapy; Humans; Immune resistance; Immune response; Immune system; Immune System - immunology; Immunosurveillance; Immunotherapy; Immunotherapy - methods; Kinases; Metabolism; Metastasis; Neoplasms - immunology; Neoplasms - therapy; Phagocytosis; Prostate; Protein synthesis; Proteins; Review; Tumor; Tumor cells; Tumor immunotherapy; Tumors; Tumor; Tumor immunotherapy; Immune resistance; Immune response; Autophagy

Autophagy is a genetically well-controlled cellular process that is tightly controlled by a set of core genes, including the family of autophagy-related genes (ATG). Autophagy is a "double-edged sword" in tumors. It can promote or suppress tumor development, which depends on the cell and t...