Identifying clinical subgroups in IgG4-related disease patients using cluster analysis and IgG4-RD composite score

• Published in: Arthritis research & therapy Vol. 22; no. 1; pp. 7 - 13
• Main Authors: Li, Jieqiong, Peng, Yu, Zhang, Yuelun, Zhang, Panpan, Liu, Zheng, Lu, Hui, Peng, Linyi, Zhu, Liang, Xue, Huadan, Zhao, Yan, Zeng, Xiaofeng, Fei, Yunyun, Zhang, Wen
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 10.01.2020; BioMed Central; BMC
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Allergy; Arthritis; Blood tests; Child; Cluster Analysis; Diagnosis; Diseases; Eigenvalues; Female; Health aspects; Humans; IgG4-RD CS; IgG4-related disease; Immunoglobulin G; Immunoglobulin G4-Related Disease - classification; Immunoglobulin G4-Related Disease - immunology; Immunoglobulin G4-Related Disease - pathology; Immunoglobulins; Immunologic deficiency syndromes; Laboratories; Laboratory test; Lymphocytes; Male; Medical research; Medical tests; Middle Aged; Organs involved; Patients; Phenotypes; Regression analysis; Statistical analysis; Young Adult; China; Cluster analysis; Organs involved; Laboratory test; IgG4-RD CS; IgG4-related disease

To explore the clinical patterns of patients with IgG4-related disease (IgG4-RD) based on laboratory tests and the number of organs involved. Twenty-two baseline variables were obtained from 154 patients with IgG4-RD. Based on principal component analysis (PCA), patients with IgG4-RD were classified...