Potential Impact of Prosthetic Biomaterials on the Periodontium: A Comprehensive Review

The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the importance of prosthetic restorative materials on the condition of the periodontium, the changes that occur in the composition of the subgingiva...

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Published inMolecules (Basel, Switzerland) Vol. 28; no. 3; p. 1075
Main Authors Alarcón-Sánchez, Mario Alberto, Heboyan, Artak, Fernandes, Gustavo Vicentis de Oliveira, Castro-Alarcón, Natividad, Romero-Castro, Norma Samanta
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 20.01.2023
MDPI
Subjects
Bacteria
Biofilms
Biological products
Biomarkers
Biomedical materials
Care and treatment
Ceramics
Composition
Cytokines
Diagnosis
fixed prosthesis
Genotype & phenotype
Gingival Crevicular Fluid
Health aspects
Humans
Inflammation
Materials
Microbiota
Microbiota (Symbiotic organisms)
Patients
periodontal biomarkers and gingival crevicular fluid
Periodontal disease
periodontal health
Periodontal Ligament
Periodontium
Prostheses
prosthetic biomaterials
Prosthodontics
Review
Risk factors
subgingival microbiota
Mexico
periodontal biomarkers and gingival crevicular fluid
fixed prosthesis
periodontal health
subgingival microbiota
prosthetic biomaterials
Online AccessGet full text
ISSN1420-3049
1420-3049
DOI10.3390/molecules28031075

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Abstract The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the importance of prosthetic restorative materials on the condition of the periodontium, the changes that occur in the composition of the subgingival microbiota and the levels of inflammatory markers in gingival crevicular fluid. Articles on the influence of different prosthetic restorative materials on subgingival microbiota and proinflammatory cytokines were searched for using the keywords “prosthetic biomaterials”, “fixed prosthesis”, “periodontal health”, “subgingival microbiota”, “periodontal biomarkers” and “gingival crevicular fluid” in PubMed/Medline, Science Direct, Scopus and Google Scholar. The type of material used for prosthesis fabrication together with poor marginal and internal fit can result in changes in the composition of the subgingival microbiota, as well as increased accumulation and retention of dentobacterial plaque, thus favoring the development of periodontal disease and prosthetic treatment failure. Biological markers have helped to understand the inflammatory response of different prosthetic materials on periodontal tissues with the main purpose of improving their clinical application in patients who need them. Metal-free ceramic prostheses induce a lower inflammatory response regardless of the fabrication method; however, the use of CAD/CAM systems is recommended for their fabrication. In addition, it is presumed that metal-ceramic prostheses cause changes in the composition of the subgingival microbiota producing a more dysbiotic biofilm with a higher prevalence of periodontopathogenic bacteria, which may further favor periodontal deterioration.
AbstractList The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the importance of prosthetic restorative materials on the condition of the periodontium, the changes that occur in the composition of the subgingival microbiota and the levels of inflammatory markers in gingival crevicular fluid. Articles on the influence of different prosthetic restorative materials on subgingival microbiota and proinflammatory cytokines were searched for using the keywords "prosthetic biomaterials", "fixed prosthesis", "periodontal health", "subgingival microbiota", "periodontal biomarkers" and "gingival crevicular fluid" in PubMed/Medline, Science Direct, Scopus and Google Scholar. The type of material used for prosthesis fabrication together with poor marginal and internal fit can result in changes in the composition of the subgingival microbiota, as well as increased accumulation and retention of dentobacterial plaque, thus favoring the development of periodontal disease and prosthetic treatment failure. Biological markers have helped to understand the inflammatory response of different prosthetic materials on periodontal tissues with the main purpose of improving their clinical application in patients who need them. Metal-free ceramic prostheses induce a lower inflammatory response regardless of the fabrication method; however, the use of CAD/CAM systems is recommended for their fabrication. In addition, it is presumed that metal-ceramic prostheses cause changes in the composition of the subgingival microbiota producing a more dysbiotic biofilm with a higher prevalence of periodontopathogenic bacteria, which may further favor periodontal deterioration.The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the importance of prosthetic restorative materials on the condition of the periodontium, the changes that occur in the composition of the subgingival microbiota and the levels of inflammatory markers in gingival crevicular fluid. Articles on the influence of different prosthetic restorative materials on subgingival microbiota and proinflammatory cytokines were searched for using the keywords "prosthetic biomaterials", "fixed prosthesis", "periodontal health", "subgingival microbiota", "periodontal biomarkers" and "gingival crevicular fluid" in PubMed/Medline, Science Direct, Scopus and Google Scholar. The type of material used for prosthesis fabrication together with poor marginal and internal fit can result in changes in the composition of the subgingival microbiota, as well as increased accumulation and retention of dentobacterial plaque, thus favoring the development of periodontal disease and prosthetic treatment failure. Biological markers have helped to understand the inflammatory response of different prosthetic materials on periodontal tissues with the main purpose of improving their clinical application in patients who need them. Metal-free ceramic prostheses induce a lower inflammatory response regardless of the fabrication method; however, the use of CAD/CAM systems is recommended for their fabrication. In addition, it is presumed that metal-ceramic prostheses cause changes in the composition of the subgingival microbiota producing a more dysbiotic biofilm with a higher prevalence of periodontopathogenic bacteria, which may further favor periodontal deterioration.
The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the importance of prosthetic restorative materials on the condition of the periodontium, the changes that occur in the composition of the subgingival microbiota and the levels of inflammatory markers in gingival crevicular fluid. Articles on the influence of different prosthetic restorative materials on subgingival microbiota and proinflammatory cytokines were searched for using the keywords “prosthetic biomaterials”, “fixed prosthesis”, “periodontal health”, “subgingival microbiota”, “periodontal biomarkers” and “gingival crevicular fluid” in PubMed/Medline, Science Direct, Scopus and Google Scholar. The type of material used for prosthesis fabrication together with poor marginal and internal fit can result in changes in the composition of the subgingival microbiota, as well as increased accumulation and retention of dentobacterial plaque, thus favoring the development of periodontal disease and prosthetic treatment failure. Biological markers have helped to understand the inflammatory response of different prosthetic materials on periodontal tissues with the main purpose of improving their clinical application in patients who need them. Metal-free ceramic prostheses induce a lower inflammatory response regardless of the fabrication method; however, the use of CAD/CAM systems is recommended for their fabrication. In addition, it is presumed that metal-ceramic prostheses cause changes in the composition of the subgingival microbiota producing a more dysbiotic biofilm with a higher prevalence of periodontopathogenic bacteria, which may further favor periodontal deterioration.
Audience Academic
Author Heboyan, Artak
Alarcón-Sánchez, Mario Alberto
Fernandes, Gustavo Vicentis de Oliveira
Romero-Castro, Norma Samanta
Castro-Alarcón, Natividad
AuthorAffiliation 4 Department of Implantology and Oral Rehabilitation, Faculty of Dentistry, Autonomous University of Guerrero, Acapulco 39610, Guerrero, Mexico
3 Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA
2 Department of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Str. Koryun 2, Yerevan 0025, Armenia
1 Department of Microbiology, Faculty of Chemical and Biological Sciences, Autonomous University of Guerrero, Chilpancingo 39090, Guerrero, Mexico
AuthorAffiliation_xml – name: 1 Department of Microbiology, Faculty of Chemical and Biological Sciences, Autonomous University of Guerrero, Chilpancingo 39090, Guerrero, Mexico
– name: 4 Department of Implantology and Oral Rehabilitation, Faculty of Dentistry, Autonomous University of Guerrero, Acapulco 39610, Guerrero, Mexico
– name: 3 Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI 48109, USA
– name: 2 Department of Prosthodontics, Faculty of Stomatology, Yerevan State Medical University after Mkhitar Heratsi, Str. Koryun 2, Yerevan 0025, Armenia
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  givenname: Natividad
  surname: Castro-Alarcón
  fullname: Castro-Alarcón, Natividad
– sequence: 5
  givenname: Norma Samanta
  orcidid: 0000-0003-3468-6437
  surname: Romero-Castro
  fullname: Romero-Castro, Norma Samanta
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Keywords periodontal biomarkers and gingival crevicular fluid
fixed prosthesis
periodontal health
subgingival microbiota
prosthetic biomaterials
Language English
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PublicationPlace Switzerland
PublicationPlace_xml – name: Switzerland
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PublicationTitle Molecules (Basel, Switzerland)
PublicationTitleAlternate Molecules
PublicationYear 2023
Publisher MDPI AG
MDPI
Publisher_xml – name: MDPI AG
– name: MDPI
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Snippet The success of a prosthetic treatment is closely related to the periodontal health of the individual. The aim of this article was to review and present the...
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SubjectTerms Bacteria
Biofilms
Biological products
Biomarkers
Biomedical materials
Care and treatment
Ceramics
Composition
Cytokines
Diagnosis
fixed prosthesis
Genotype & phenotype
Gingival Crevicular Fluid
Health aspects
Humans
Inflammation
Materials
Microbiota
Microbiota (Symbiotic organisms)
Patients
periodontal biomarkers and gingival crevicular fluid
Periodontal disease
periodontal health
Periodontal Ligament
Periodontium
Prostheses
prosthetic biomaterials
Prosthodontics
Review
Risk factors
subgingival microbiota
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Title Potential Impact of Prosthetic Biomaterials on the Periodontium: A Comprehensive Review
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Volume 28
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