Sinonasal pathophysiology of SARS‐CoV‐2 and COVID‐19: A systematic review of the current evidence

• Published in: Laryngoscope investigative otolaryngology Vol. 5; no. 3; pp. 354 - 359
• Main Authors: Gengler, Isabelle, Wang, James C., Speth, Marlene M., Sedaghat, Ahmad R.
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.06.2020; Wiley
• Subjects: Allergy, Rhinology, and Immunology; anosmia; congestion; coronavirus; Coronaviruses; COVID-19; Disease transmission; Epidemics; Gene expression; Glycoproteins; Infections; Nose; Olfaction disorders; olfactory dysfunction; Otolaryngology; Outdoor air quality; Pandemics; paranasal sinus; Pathophysiology; Respiratory diseases; respiratory epithelium; Review; rhinorrhea; SARS; SARS‐CoV2; SARS‐CoV‐2; Severe acute respiratory syndrome coronavirus 2; sinonasal; Subject heading schemes; Systematic review; transmission; nose; rhinorrhea; COVID‐19; SARS‐CoV2; SARS; coronavirus; olfactory dysfunction; systematic review; respiratory epithelium; transmission; SARS‐CoV‐2; anosmia; sinonasal; paranasal sinus; congestion

Objective The ongoing pandemic of coronavirus disease (2019 coronavirus disease [COVID‐19]), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus, is highly contagious with high morbidity and mortality. The role of the nasal and paranasal sinus cavities is increasingly re...