The prognostic and clinicopathological significance of PD-L1 expression in patients with diffuse large B-cell lymphoma: a meta-analysis

• Published in: BMC cancer Vol. 19; no. 1; pp. 273 - 12
• Main Authors: Qiu, Liping, Zheng, Hanlu, Zhao, Xiaoying
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.03.2019; BioMed Central; BMC
• Subjects: Apoptosis; B-cell lymphoma; B7-H1 Antigen - metabolism; Bcl-6 protein; Biomarkers, Tumor - metabolism; Blood cancer; Cancer; Care and treatment; Cell death; Diagnosis; Diffuse large B-cell lymphoma; Female; Gene expression; Gene Expression Regulation, Neoplastic; Humans; Interferon Regulatory Factors - metabolism; Kinases; Ligands; Lymphocytes B; Lymphocytic leukemia; Lymphoma; Lymphoma, Large B-Cell, Diffuse - metabolism; Lymphoma, Large B-Cell, Diffuse - pathology; Male; Measurement techniques; Medical prognosis; Meta-analysis; Odds Ratio; PD-L1 protein; Prognosis; Programmed cell death receptor 1 ligand 1 (PD-L1); Proto-Oncogene Proteins c-bcl-6 - metabolism; Sensitivity analysis; Studies; Survival Analysis; Tumor cells; Tumors; Prognosis; Programmed cell death receptor 1 ligand 1 (PD-L1); Diffuse large B-cell lymphoma; Meta-analysis

Programmed cell death receptor 1 ligand 1 (PD-L1) expression in various tumors, including hematologic malignancies, has recently become a research topic of great interest. We performed a meta-analysis to evaluate the prognostic and clinicopathological value of PD-L1 expressed in tumor cells of patie...