Neurolymphomatosis of the lumbosacral plexus and its branches: case series and literature review
Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. We present 3 examples of invasion o...
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Published in | BMC cancer Vol. 19; no. 1; p. 1149 |
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Main Authors | , , , , |
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Language | English |
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27.11.2019
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Abstract | Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma.
We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response.
The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. |
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AbstractList | Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. Abstract Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. Case presentation We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. Conclusion The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. Abstract Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. Case presentation We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. Conclusion The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. Case presentation We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. Conclusion The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. Keywords: Neurolymphomatosis, Lumbosacral, Neuropathy, B-cell lymphoma, MR neurography Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. Case presentation We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. Conclusion The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. BACKGROUNDNeurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. CASE PRESENTATIONWe present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. CONCLUSIONThe diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a particularly difficult diagnostic dilemma when it is the presenting focal manifestation of occult lymphoma. We present 3 examples of invasion of the lumbosacral plexus and its branches. These cases demonstrate a protean clinical picture with regards to the time relationship to the clinical course of lymphoma and the neuroanatomical extent of lumbosacral plexus invasion. We demonstrate the complementary role of different imaging modalities. A review of the literature summarizes 23 reports where lumbosacral plexus invasion was the index manifestation, at the time of first diagnosis or recurrence of lymphoma. This series confirms the strong preponderance of B-cell type (92%). There is a marked predilection for involvement of the sciatic nerve (74%), either focally or in a longitudinally extensive fashion, from the ischium to the popliteal fossa. There can also be restricted and discrete involvement of tibial and fibular branches. In recent years, ultrasound and CT have been given a more limited role, as screening tools or as a guide for biopsy. MRI neurography and PET-CT have become leading diagnostic modalities for diagnosis, staging and assessment of treatment response. The diagnosis of NL may be challenging, and it was once only reached at autopsy. Improved diagnostic imaging of focal or even asymptomatic disease offers new hope for earlier diagnosis and successful targeted therapy. |
ArticleNumber | 1149 |
Audience | Academic |
Author | Samaan, Sam Bourque, Pierre R Warman-Chardon, Jodi Torres, Carlos Sampaio, Marcos Loreto |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31775683$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1016/j.ejrad.2010.11.020 10.1016/j.clinimag.2016.08.014 10.1007/s10072-013-1499-1 10.1097/00000478-199009000-00011 10.2967/jnumed.109.067892 10.3171/jns.1983.59.1.0131 10.1002/hon.837 10.1016/j.clml.2017.10.007 10.1212/WNL.0000000000001900 10.1182/blood-2009-12-258210 10.3174/ajnr.A2257 10.1097/PPO.0b013e31826c5ad5 10.1097/01.pas.0000155166.86409.d2 10.1038/bjc.2015.94 10.1136/jnnp.47.11.1219 10.2214/AJR.13.12403 10.1017/cjn.2017.282 10.1227/00006123-199506000-00024 10.1053/j.jfas.2017.07.004 10.1097/RLU.0000000000000982 10.1007/s00401-012-0954-z 10.1136/jnnp-2014-309697 10.1007/s00330-017-4976-8 10.1093/brain/awt193 10.3171/foc.2007.22.6.7 10.1212/WNL.0000000000001880 10.1056/NEJMcps1613804 10.1111/j.1600-0609.2010.01477.x 10.3348/jksr.2016.75.5.399 10.1212/01.wnl.0000338598.07063.5b 10.3171/jns.2000.92.1.0165 10.1215/15228517-5-2-104 |
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Keywords | Neurolymphomatosis MR neurography Lumbosacral Neuropathy B-cell lymphoma |
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References | M Weiler-Sagie (6365_CR24) 2010; 51 SK Thawait (6365_CR23) 2011; 32 V Eusebi (6365_CR29) 1990; 14 JL Hornick (6365_CR8) 2005; 29 EL Lee (6365_CR12) 2016; 75 RM Kwee (6365_CR22) 2014; 203 S Grisariu (6365_CR2) 2010; 115 SC Kosa (6365_CR19) 2009; 72 T Koyama (6365_CR17) 2010; 85 A Chhabra (6365_CR21) 2018; 28 YB Challenor (6365_CR10) 1984; 47 M Kanamori (6365_CR28) 1995; 36 F Roncaroli (6365_CR27) 1997; 40 F Cabanillas (6365_CR33) 2017; 17 SK Powers (6365_CR20) 1983; 59 PR Bourque (6365_CR3) 2018; 45 RP Rush (6365_CR5) 2017; 377 T Singh (6365_CR14) 2007; 22 EK Mathey (6365_CR9) 2015; 86 A Smith (6365_CR32) 2015; 112 A Moussa (6365_CR11) 2018; 57 P Gykiere (6365_CR30) 2016; 41 M Tomita (6365_CR4) 2013; 136 JM Baehring (6365_CR6) 2012; 18 FO Walker (6365_CR18) 2015; 85 FJ Rodriguez (6365_CR7) 2012; 123 LM Wu (6365_CR25) 2012; 81 A Quinones-Hinojosa (6365_CR26) 2000; 92 M Lin (6365_CR31) 2008; 26 T Saito (6365_CR15) 2014; 35 J Vijayan (6365_CR16) 2015; 85 PA Sideras (6365_CR13) 2016; 40 JM Baehring (6365_CR1) 2003; 5 |
References_xml | – volume: 81 start-page: 303 issue: 2 year: 2012 ident: 6365_CR25 publication-title: Eur J Radiol doi: 10.1016/j.ejrad.2010.11.020 contributor: fullname: LM Wu – volume: 40 start-page: 1253 issue: 6 year: 2016 ident: 6365_CR13 publication-title: Clin Imaging doi: 10.1016/j.clinimag.2016.08.014 contributor: fullname: PA Sideras – volume: 35 start-page: 103 issue: 1 year: 2014 ident: 6365_CR15 publication-title: Neurol Sci doi: 10.1007/s10072-013-1499-1 contributor: fullname: T Saito – volume: 14 start-page: 881 issue: 9 year: 1990 ident: 6365_CR29 publication-title: Am J Surg Pathol doi: 10.1097/00000478-199009000-00011 contributor: fullname: V Eusebi – volume: 51 start-page: 25 issue: 1 year: 2010 ident: 6365_CR24 publication-title: J Nucl Med doi: 10.2967/jnumed.109.067892 contributor: fullname: M Weiler-Sagie – volume: 59 start-page: 131 issue: 1 year: 1983 ident: 6365_CR20 publication-title: J Neurosurg doi: 10.3171/jns.1983.59.1.0131 contributor: fullname: SK Powers – volume: 40 start-page: 618 issue: 3 year: 1997 ident: 6365_CR27 publication-title: Neurosurgery. contributor: fullname: F Roncaroli – volume: 26 start-page: 43 issue: 1 year: 2008 ident: 6365_CR31 publication-title: Hematol Oncol doi: 10.1002/hon.837 contributor: fullname: M Lin – volume: 17 start-page: 783 issue: 12 year: 2017 ident: 6365_CR33 publication-title: Clin Lymphoma Myeloma Leuk doi: 10.1016/j.clml.2017.10.007 contributor: fullname: F Cabanillas – volume: 85 start-page: 746 issue: 9 year: 2015 ident: 6365_CR18 publication-title: Neurology. doi: 10.1212/WNL.0000000000001900 contributor: fullname: FO Walker – volume: 115 start-page: 5005 issue: 24 year: 2010 ident: 6365_CR2 publication-title: Blood. doi: 10.1182/blood-2009-12-258210 contributor: fullname: S Grisariu – volume: 32 start-page: 1365 issue: 8 year: 2011 ident: 6365_CR23 publication-title: AJNR Am J Neuroradiol doi: 10.3174/ajnr.A2257 contributor: fullname: SK Thawait – volume: 18 start-page: 463 issue: 5 year: 2012 ident: 6365_CR6 publication-title: Cancer J doi: 10.1097/PPO.0b013e31826c5ad5 contributor: fullname: JM Baehring – volume: 29 start-page: 845 issue: 7 year: 2005 ident: 6365_CR8 publication-title: Am J Surg Pathol doi: 10.1097/01.pas.0000155166.86409.d2 contributor: fullname: JL Hornick – volume: 112 start-page: 1575 issue: 9 year: 2015 ident: 6365_CR32 publication-title: Br J Cancer doi: 10.1038/bjc.2015.94 contributor: fullname: A Smith – volume: 47 start-page: 1219 issue: 11 year: 1984 ident: 6365_CR10 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.47.11.1219 contributor: fullname: YB Challenor – volume: 203 start-page: 1303 issue: 6 year: 2014 ident: 6365_CR22 publication-title: AJR Am J Roentgenol doi: 10.2214/AJR.13.12403 contributor: fullname: RM Kwee – volume: 45 start-page: 137 issue: 2 year: 2018 ident: 6365_CR3 publication-title: Can J Neurol Sci doi: 10.1017/cjn.2017.282 contributor: fullname: PR Bourque – volume: 36 start-page: 1203 issue: 6 year: 1995 ident: 6365_CR28 publication-title: Neurosurgery. doi: 10.1227/00006123-199506000-00024 contributor: fullname: M Kanamori – volume: 57 start-page: 167 issue: 1 year: 2018 ident: 6365_CR11 publication-title: J Foot Ankle Surg doi: 10.1053/j.jfas.2017.07.004 contributor: fullname: A Moussa – volume: 41 start-page: 142 issue: 2 year: 2016 ident: 6365_CR30 publication-title: Clin Nucl Med doi: 10.1097/RLU.0000000000000982 contributor: fullname: P Gykiere – volume: 123 start-page: 295 issue: 3 year: 2012 ident: 6365_CR7 publication-title: Acta Neuropathol doi: 10.1007/s00401-012-0954-z contributor: fullname: FJ Rodriguez – volume: 86 start-page: 973 issue: 9 year: 2015 ident: 6365_CR9 publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp-2014-309697 contributor: fullname: EK Mathey – volume: 28 start-page: 698 issue: 2 year: 2018 ident: 6365_CR21 publication-title: Eur Radiol doi: 10.1007/s00330-017-4976-8 contributor: fullname: A Chhabra – volume: 136 start-page: 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Snippet | Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and represents a... Abstract Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma... Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and... BACKGROUNDNeurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma and... Abstract Background Neurolymphomatosis (NL) is a direct process of invasion of peripheral nerves by lymphoma. It occurs in roughly 5% of patients with lymphoma... |
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SubjectTerms | Age Aged Anatomy Ankle Autopsy B-cell lymphoma Biopsy Bone marrow Case Report Chemotherapy Computed tomography Diagnosis Female Fluorodeoxyglucose F18 Humans Literature reviews Lumbosacral Lumbosacral Plexus - pathology Lymphocytes B Lymphoma Magnetic Resonance Imaging Male Middle Aged MR neurography Neoplasm Staging Neurolymphomatosis Neurolymphomatosis - diagnosis Neurolymphomatosis - therapy Neuropathy Non-Hodgkin's lymphomas Peripheral nerves Positron emission tomography Positron Emission Tomography Computed Tomography Radiation therapy Sciatic nerve Ultrasonic imaging Ultrasonography Ultrasound |
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Title | Neurolymphomatosis of the lumbosacral plexus and its branches: case series and literature review |
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