Identification of a novel mechanism of action of bovine IgG antibodies specific for Staphylococcus aureus

• Published in: Veterinary research (Paris) Vol. 49; no. 1; p. 22
• Main Authors: Furukawa, Mutsumi, Yoneyama, Hiroshi, Hata, Eiji, Iwano, Hidetomo, Higuchi, Hidetoshi, Ando, Tasuke, Sato, Mika, Hayashi, Tomohito, Kiku, Yoshio, Nagasawa, Yuya, Niimi, Kanae, Usami, Katsuki, Ito, Kumiko, Watanabe, Kouichi, Nochi, Tomonori, Aso, Hisashi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 26.02.2018; BioMed Central; BMC
• Subjects: agglutination; antibodies; antigens; bacterial adhesion; bovine mastitis; Care and treatment; Cattle; Control; dairy industry; financial economics; genes; Health aspects; Immunoglobulin G; in vitro culture; Inflammation; Life Sciences; mechanism of action; membrane proteins; microbial growth; mutants; pathogens; phagocytes; polysaccharides; sortase A; Staphylococcus aureus; Staphylococcus aureus infections; Vaccination; vaccines; veterinary medicine

Staphylococcus aureus is a major pathogen that causes subclinical mastitis associated with huge economic losses to the dairy industry. A few vaccines for bovine mastitis are available, and they are expected to induce the production of S. aureus-specific antibodies that prevent bacterial adherence to...