Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site - Kanekiyo, Masaru; Bu, Wei; Joyce, M. Gordon; Meng, Geng; Whittle, James R.R.; Baxa, Ulrich; Yamamoto, Takuya; Narpala, Sandeep; Todd, John-Paul; Rao, Srinivas S.; McDermott, Adrian B.; Koup, Richard A.; et al. (Cell, 2015)
Keywords: animal models; Animals; Antibodies, Neutralizing - immunology; complement; Crystallography, X-Ray; Drug Design; Female; glycoproteins; Herpesvirus 4, Human; Herpesvirus Vaccines - chemistry; Herpesvirus Vaccines - genetics; Herpesvirus Vaccines - immunology; Herpesvirus Vaccines - isolation & purification; Human gammaherpesvirus 4; immunity; Macaca fascicularis; Mice; Mice, Inbred BALB C; nanoparticles; Nanoparticles - chemistry; Nanoparticles - ultrastructure; neoplasms; neutralization; neutralizing antibodies; Primates; Receptors, Complement 3d - chemistry; Receptors, Complement 3d - immunology; Recombinant Proteins - chemistry; Recombinant Proteins - genetics; Recombinant Proteins - immunology; Recombinant Proteins - isolation & purification; vaccine development; vaccines; viruses