Microbiomic differences in tumor and paired-normal tissue in head and neck squamous cell carcinomas

• Published in: Genome medicine Vol. 9; no. 1; p. 14
• Main Authors: Wang, Hannah, Funchain, Pauline, Bebek, Gurkan, Altemus, Jessica, Zhang, Huan, Niazi, Farshad, Peterson, Charissa, Lee, Walter T, Burkey, Brian B, Eng, Charis
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 07.02.2017; BioMed Central
• Subjects: Actinomyces; Aged; Analysis; Bacteria - isolation & purification; Carcinoma, Squamous Cell - microbiology; Care and treatment; Female; Gastrointestinal Microbiome; Head and neck cancer; Head and Neck Neoplasms - microbiology; Humans; Male; Microbiota (Symbiotic organisms); Middle Aged; Mouth - microbiology; Risk factors; Tumor removal; Bacteria; Head and neck squamous cell carcinoma (HNSCC); Microbiome

While the role of the gut microbiome in inflammation and colorectal cancers has received much recent attention, there are few data to support an association between the oral microbiome and head and neck squamous cell carcinomas. Prior investigations have been limited to comparisons of microbiota obt...